Massachusetts General Hospital (MGH) researchers have used vascular precursor cells derived from human induced pluripotent stem cells (iPSCs) to generate, in an animal model, functional blood vessels that lasted as long as nine months. In their report being published in PNAS Early Edition, the investigators describe using iPSCs – reprogrammed adult cells that have many of the characteristics of embryonic stem cells – from both healthy adults and from individuals with type 1 diabetes to generate blood vessels on the outer surface of the brain or under the skin of mice.
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