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Quadratic leap in detecting smallest unit of genetic change

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Scientists at Rice University and the University of Washington (UW) this week unveiled a groundbreaking new method for detecting minute changes known as single nucleotide polymorphisms (SNPs) in the human genome. The human genome has more than 6 billion base pairs, and one of the revelations of modern genomics is that even the slightest change in the sequence—a single-nucleotide difference—can have profound effects.

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