Researchers have identified a genomic variant strongly associated with sensitivity to the sun, brown hair, blue eyes – and freckles. In the study of Icelanders the researchers uncovered an intricate pathway involving the interspersed DNA sequence, or non-coding region, of a gene that is among a few dozen that are associated with human pigmentation traits. The study by an international team including researchers from the National Institutes of Health was reported in the Nov. 21, 2013, online edition of the journal Cell.
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