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Researchers identify variation in gene PLD3 can increase risk of late-onset Alzheimer’s disease

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(Medical Xpress)—A new study, part-funded by the Medical Research Council (MRC), the Wellcome Trust and Alzheimer's Research UK, has shown that a fault in a gene called phospholipase D3 (PLD3) can contribute to the overproduction of amyloid-beta in the brain. Increased levels of this chemical are associated with an increased chance of developing Alzheimer's disease and the results show that, in certain cases, this can double an individual's risk.

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