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Study finds progenitor cells engage in 'apical abscission' to differentiate into neurons

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(Medical Xpress)—A pair of researchers working at the University of Dundee in the U.K. has discovered a new step during vertebrate neurogenesis—the process by which progenitor cells develop into neurons in embryos. In their paper published in the journal Science, Raman Das and Kate Storey describe how they used high-resolution live-cell imaging to observe early stage vertebrae brain development and in so doing discovered the previously unknown step during neurogenesis which they have called "apical abscission"—where precursor cells must leave the neural tube in which they develop to grow into different parts of the nervous system. In the same journal edition Samuel Tozer and Xavier Morin describe the process further in a Perspective piece.

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