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Autism linked to increased genetic change in regions of genome instability

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(Medical Xpress)—Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the chances that a child will develop autism—a behavioral disorder that affects about 1 of every 88 children in the United States, according to the Centers for Disease Control.

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