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Study suggests way to fight therapy resistant leukemia by blocking DNA repair

New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of...

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Gene regulator is key to healthy retinal development and good vision in...

Scientists are developing a clearer picture of how visual systems develop in mammals. The findings offer important clues to the origin of retinal disorders later in life.

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Investigational malaria vaccine found safe and protective

An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an...

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Study shows microRNAs can trigger lymphomas

A small group of immune-regulating molecules, when overproduced even moderately, can trigger the blood cancers known as lymphomas, according to a new study led by scientists from The Scripps Research...

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Researchers extend human epigenomic map

Ten years ago, scientists announced the end of the Human Genome Project, the international attempt to learn which combination of four nucleotides—adenine, thymine, cytosine, and guanine—is unique to...

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With early, obvious benefit of a targeted cancer drug, should expensive...

Generally, FDA-approved clinical trials progress through three phases: the first shows safety, the second starts to explore effects and the third seeks to prove a drug's superiority over existing...

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Autism affects different parts of the brain in women and men

Autism affects different parts of the brain in females with autism than males with autism, a new study reveals. The research is published today in the journal Brain as an open-access article.

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Study monitors DNA breaks and chromosome translocations in real time

(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.

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Researchers show how brain's micro-environment fuels metastatic tumor growth

When a cancer cell breaks off from a tumor in the breast, lung or other part of the body and flows through the bloodstream to the brain, trouble erupts. Like a dandelion seed landing in the most...

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Formula-fed babies may be more susceptible to chronic disease, study finds

(Medical Xpress)—Formula-fed infants experience metabolic stress that could make them more susceptible than breast-fed infants to a wide range of health issues such as obesity, diabetes, liver problems...

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Study finds that some depressed adolescents are at higher risk for developing...

Some adolescents who suffer with symptoms of depression also may be at risk for developing anxiety, according to a new study of children's mental health.

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New inhibitor blocks the oncogenic protein KRAS

One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite decades of active agent research, efforts to...

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Low childhood conscientiousness predicts adult obesity

Results from a longitudinal study show that children who exhibit lower conscientiousness (e.g., irresponsible, careless, not persevering) could experience worse overall health, including greater...

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How parents see themselves may affect their child's brain and stress level

A mother's perceived social status predicts her child's brain development and stress indicators, finds a study at Boston Children's Hospital. While previous studies going back to the 1950s have linked...

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New study suggests chronic cocaine use causes profound metabolic changes,...

Chronic cocaine use may reduce the body's ability to store fat, new research from the University of Cambridge suggests.

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How players strike keys depends on how muscles are used for keystrokes that...

Researchers have long been aware of a phenomenon in speech called coarticulation, in which certain sounds are produced differently depending on the sounds that come before or after them. For example,...

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Ultrasound device might be a mood booster

(HealthDay)—Imagine putting on special ultrasound headphones and cheering up when you're feeling blue. Such a device could someday be an option, a new small study suggests.

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Nanodrug targeting breast cancer cells from the inside adds weapon: Immune...

A unique nanoscale drug that can carry a variety of weapons and sneak into cancer cells to break them down from the inside has a new component: a protein that stimulates the immune system to attack...

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Macrophage proliferation appears to drive progression of atherosclerosis

New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes. In a report being published online in Nature Medicine,...

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Disease gene discovered for frequent epilepsy in childhood

More than 50 million people worldwide have epilepsy, with a third of these being children. The most common forms of epilepsy in children occur without any apparent trigger and only affect certain...

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