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Common blood cancer may be initiated by single mutation in bone cells

Acute myeloid leukemia (AML) is a blood cancer, but for many patients the cancer may originate from an unusual source: a mutation in their bone cells.

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Exposure to cold temperatures can help boost weight loss

Regular exposure to mild cold may be a healthy and sustainable way to help people lose weight, according to researchers writing in the Cell Press publication Trends in Endocrinology & Metabolism on...

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Stanford researchers reveal more about how our brains control our arms

Ready, set, go. Sometimes that's how our brains work. When we anticipate a physical act, such as reaching for the keys we noticed on the table, the neurons that control the task adopt a state of...

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Study could lead to 'liquid biopsy' tests for bladder cancer

Findings from a Loyola University Medical Center study ultimately could lead to tests to screen for and diagnose bladder cancer.

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Possible new druggable target in Ewing's Sarcoma

Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this...

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Researchers develop risk calculator to predict survival in heart failure...

A UCLA team has developed an easy-to-use "risk calculator" that helps predict heart failure patients' chances of survival for up to five years and assists doctors in determining whether more or less...

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Estrogen promotes blood-forming stem cell function

Scientists have known for years that stem cells in male and female sexual organs are regulated differently by their respective hormones. In a surprising discovery, researchers at the Children's Medical...

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New genetic mutations shed light on schizophrenia

Researchers from the Broad Institute and several partnering institutions have taken a closer look at the human genome to learn more about the genetic underpinnings of schizophrenia. In two studies...

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Gene therapy leads to robust improvements in animal model of fatal muscle...

Preclinical studies show that gene therapy can improve muscle strength in small- and large-animal models of a fatal congenital pediatric disease known as X-linked myotubular myopathy. The results,...

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The unexpected power of baby math: Adults still think about numbers like kids

Children understand numbers differently than adults. For kids, one and two seem much further apart then 101 and 102, because two is twice as big as one, and 102 is just a little bigger than 101. It's...

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Unprecedented structural insights: NMDA receptors can be blocked to limit...

Structural biologists at Cold Spring Harbor Laboratory (CSHL) and collaborators at Emory University have obtained important scientific results likely to advance efforts to develop new drugs targeting...

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Scientists offer new insight into neuron changes brought about by aging

How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer's and Parkinson's disease.

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Dissolving 'scaffolds' could help treat leg artery disease

(HealthDay)—Drug-coated "scaffolds" that are placed in the arteries and then melt away over time could offer a new treatment for people with painfully clogged leg arteries, an early study suggests.

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Alzheimer's drugs fail, but lessons are learned

Dr. Stephen Salloway pulls no punches in describing the results of two clinical trials of the Alzheimer's drug bapineuzumab that he helped to lead. The antibody failed to produce cognitive improvement...

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Computer simulation of blood vessel growth (w/ video)

University of Utah bioengineers showed that tiny blood vessels grow better in the laboratory if the tissue surrounding them is less dense. Then the researchers created a computer simulation to predict...

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Humans can use smell to detect levels of dietary fat

New research from the Monell Center reveals humans can use the sense of smell to detect dietary fat in food. As food smell almost always is detected before taste, the findings identify one of the first...

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Study shows one in five women with ovarian cancer has inherited predisposition

(Medical Xpress)—A new study conservatively estimates that one in five women with ovarian cancer has inherited genetic mutations that increase the risk of the disease, according to research at...

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Idelalisib shows promise in treating indolent non-Hodgkin lymphomas

Slow-growing, or indolent, non-Hodgkin lymphomas are difficult to treat, with most patients relapsing repeatedly and the disease becoming increasingly resistant to therapy over time.

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New diagnosis rules could lead to drop in autism numbers

(HealthDay)—Stricter new criteria for autism may change how frequently the condition is diagnosed, a new study suggests.

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Blood vessel treatment might reduce symptoms of enlarged prostate

(HealthDay)—A new nonsurgical treatment for enlarged prostate might help ease symptoms such as frequent urination at night, Brazilian researchers report.

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