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Study maps human metabolism in health and disease

Scientists have produced an instruction manual for the human genome that provides a framework to better understand the relationship between an individual's genetic make-up and their lifestyle.

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Cancer vaccines self-sabotage, channel immune attack to injection site

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University...

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Proteins with mutations in 'prion-like' segments considered candidates for...

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the...

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Scientists identify 'clean-up' snafu that kills brain cells in Parkinson's...

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which...

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Study finds how to shutdown cancer's powerful master protein

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long...

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International consortium builds 'Google Map' of human metabolism

Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual...

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Seven genetic risk factors found to be associated with age-related macular...

An international group of researchers has discovered seven new regions of the human genome—called loci—that are associated with increased risk of age-related macular degeneration (AMD), a leading cause...

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Researchers describe first 'functional HIV cure' in an infant

A team of researchers from Johns Hopkins Children's Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School describe the first case of a so-called...

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'Shelf life' of blood? Shorter than we think

A small study from Johns Hopkins adds to the growing body of evidence that red blood cells stored longer than three weeks begin to lose the capacity to deliver oxygen-rich cells where they may be most...

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Parkinson's brain rhythms suggest better way to treat disease with deep brain...

A team of scientists and clinicians at UC San Francisco has discovered how to detect abnormal brain rhythms associated with Parkinson's by implanting electrodes within the brains of people with the...

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Why your brain tires when exercising

A marathon runner approaches the finishing line, but suddenly the sweaty athlete collapses to the ground. Everyone probably assumes that this is because he has expended all energy in his muscles. What...

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Functional electrical stimulation cycling promotes physical, neurological...

(Medical Xpress)—A new study by Kennedy Krieger Institute's International Center for Spinal Cord Injury finds that long-term lower extremity functional electrical stimulation (FES) cycling, as part of...

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HIV infection appears associated with increased heart attack risk

A study that analyzed data from more than 82,000 veterans suggests that infection with the human immunodeficiency virus (HIV) was associated with an increased risk of acute myocardial infarction (AMI,...

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Protein synthesis blocker may hold key to reducing effects of traumatic events

Reducing fear and stress following a traumatic event could be as simple as providing a protein synthesis blocker to the brain, report a team of researchers from McLean Hospital, Harvard Medical School,...

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How the brain loses and regains consciousness (w/ video)

Since the mid-1800s, doctors have used drugs to induce general anesthesia in patients undergoing surgery. Despite their widespread use, little is known about how these drugs create such a profound loss...

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Stress hormone foreshadows postpartum depression in new mothers

Women who receive strong social support from their families during pregnancy appear to be protected from sharp increases in a particular stress hormone, making them less likely to develop postpartum...

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Pharmaceutical advertising down but not out, study says

The pharmaceutical industry has pulled back on marketing to physicians and consumers, yet some enduring patterns persist. According to a new study led by researchers at the Johns Hopkins Bloomberg...

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A vaccine that works in newborns? Promising compound may help protect babies...

The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston...

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Single gene might explain dramatic differences among people with schizophrenia

Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new...

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'Mean girls' be warned: Ostracism cuts both ways

If you think giving someone the cold shoulder inflicts pain only on them, beware. A new study shows that individuals who deliberately shun another person are equally distressed by the experience.

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